hake bottle well and drink contents at a comfortable yet steady pace. For your comfort, wait 15 minutes and then drink 16 oz of water. If you weigh more than 180 lbs, drink 32 oz of water instead. HELPFUL HINTS Those who are serious about a cleanse use INSURANCE capsules before using Rely Detox. While using product, urinate frequently. Do not eat large meals before using product. Avoid unwanted toxins. Drink plenty of water on a daily basis.